Beta-Blockers: Mechanism, Uses, And Side-Effects



It often happens that doctors to explain your symptoms and treatment, and you stand there like you’ll never be able to decipher their coded lingo. As much as we think that it isn’t possible for us to know the titbits of the biological glossary, it isn’t true. With little concentrated efforts, we might be able to grasp, for instance, why are you prescribed with beta-blockers! Here is a little something about the beta-blockers!

 

Beta-Blockers- The Definition And Mechanism

In simple terms, beta-blockers are a group of drugs that target the ‘fight or flight’ response of our body to prevent heart attacks.

But if you are looking to understand the mechanism of beta-blockers, here it is:

Beta-blockers are also referred as beta-adrenergic blocking agents. Staying true to its name, this group of drugs doesn’t let, or rather, block the neurotransmitters epinephrine and norepinephrine from binding to the beta receptors.

These neurotransmitters are responsible for alerting your mind of any physical, mental, or emotional excitement/danger. The adrenaline secretion directs your flight or fight situations which can be traumatic causing the heart to beat fast leading to a failure. Beta-blockers don’t let this happen!

It prevents the neurotransmitters from binding to the receptors and blocks the effects of adrenaline. The pressure that adrenaline might have put on the heart in difficult situations increasing the blood flow is blocked which in turn helps the heart to relax and beat in rhythm. If this remains consistent, the heart may have an improved pumping mechanism.


Uses Of Beta-Blockers

Although beta-blockers are known for its use for heart conditions, they are not limited to that. They manage several health conditions which are:

       Heart failure
       Hypertension
       Cardiac arrhythmias
       High coronary artery disease risk
       Diabetes
       Myocardial infarction
       Angina pectoris

Some of the off-label uses of beta-blockers include:

       Glaucoma
       Migraine
       Parkinson tremor
       Hyperthyroidism
       Fibromyalgia
       Atrial fibrillation

Downsides of Using Beta-Blockers

Even though beta-blockers are well received by the system of the patients, there is a probability of some side-effects. The most common side-effects of using beta-blockers are diarrhea, nausea, vomiting, stomach cramps, muscle cramps, blurred vision, fatigue, and rash.

It is quite an irony that the medication used for treating heart condition is also susceptible to produce side-effects related to heart such as hypotension, bradycardia, and heart failure. Hyperglycemia and hypoglycemia have also made it to the list of beta-blockers side-effects.

Interestingly, these were the effects of using these drugs. However, if you are already on these drugs and stop taking them abruptly, then its absence in the system tends to cause withdrawal symptoms such as:

       Chest pain
       Heart failure
       Angina
       Nightmares
       Headache
       Depression
       Sexual dysfunction

Yes, traditional medications come with these risks. There are other ways to deal with the heart conditions including physical training under observation, certain foods, etc. If you are living in a liberal state that allows the use of CBD oil products for heart conditions, you can go for medical marijuana as well.

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